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Xu, S., Grande, F., Garofalo, A

[DOI] [PMC free article] [PubMed] [Google Scholar] 163.Wright K.P., Trimarchi J.R., Allsworth J., Keefe D

[1] Around 2030% of East Asians carry the rs671 (ALDH2*2) allele on chromosome 12, which results in a less functional acetaldehyde dehydrogenase enzyme, responsible for the breakdown of acetaldehyde, and accounts for most incidents of alcohol flush reaction worldwide

A total of 445 articles were evaluated using their full texts, while 358 articles were removed due to factors such as untrustworthy study designs (including case reports, ethnographies, and observational designs), patient populations, interventions, outcome measurements, sample sizes smaller than 10, or the inaccessibility of the full text