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In another RCT enrolling 80 HT patients, Jianpi-Xiaoying decoction (200 mL twice daily for 12 weeks) was more effective compared to selenium supplementation (100 g twice daily for 12 weeks) at reducing TPOAb and TGAb titers, serum levels of immune factors (IFN-, IL-4, IL-4/IFN-), and thyroid elasticity

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Neural Regen Res 15(11):2041 Makunts T, Alpatty S, Lee KC, Atayee RS, Abagyan R (2019) Proton-pump inhibitor use is associated with a broad spectrum of neurological adverse events including impaired hearing, vision, and memory