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doi: 10.1016/j.drup.2021.100743

Pathway in the brain links to glutathione homeostasis

Gliotoxin induces apoptosis in hematopoietic stem cells and human hepatic stellate cells through oxidative stress mediated by ROS, and ROS also accelerates the release of mitochondrial cytochrome c and apoptosis-inducing factors, thereby promoting apoptosis

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