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Glutaminase (GLS), as a key enzyme in tubular aminamide metabolism, has also received extensive attention

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According to neurogenic hypothesis [158-159], depression may develop due to the decreased neurogenesis in hippocampus, and antidepressants takes effect through the stimulation of neurogenesis

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Acknowledgements The present study was supported by the Research Council of Norway [grant number: 214329]

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Moreover, glutathione transferases (GSTs) aid in the detoxification process by catalyzing the conjugation of glutathione to electrophilic compounds, namely in the detoxification of xenobiotics [4]

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