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The 70% of glaucoma cases are caused by elevated IOP, but it is clear that different molecular mechanisms are involved, such as oxidative stress, glutamate toxicity, neurotrophin deprivation, mitochondrial dysfunction, ischemia/hypoxia processes, protein misfolding, autoimmunity, dysfunction of autophagy processes, vascular dysregulation or neuroinflammation, which may also be responsible for RGC degeneration and death in cases of non-elevated IOP (Chang and Goldberg, 2012

When vitamins E, C or N-acetyl cysteine were examined, there was no statistically significant difference among them

417,418 G i/o family proteins can also increase PI3K expression levels and activate the PI3K/Akt signaling pathway, promoting neutrophil functions other than chemotaxis

These findings were validated by a systematic review assessing the relationship between dietary habits and GERD risk (Reference Heidarzadeh-Esfahani, Soleimani and Hajiahmadi86)