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Mitigation of oxidative damage in HCs alone is sufficient to block GSDMD-associated signaling The AAV.PHP.eB vector, when loaded with a CMV promoter, can transfect HCs with high efficiency but exhibits scattered transfection in SCs, particularly in the basal turn (Supplementary Fig

and ergothioneine has alternately been suggested as a vitamin (5) , longevity vitamin (8) and nutraceutical (6)

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Suppression of normally occurring reactive astrogliosis worsens neurological outcome and inhibits postlesional plasticity, regeneration and repair, as well as a restoration of the blood-brain barrier, which all determine functional tissue remodelling and post-traumatic rehabilitation