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This is because TRAIL-induced cell death is completely inhibited by the caspase 8 inhibitor while the inhibitor did not block TcdA-induced cell death

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The term was first introduced in 1963 to refer to a group of soft tissue tumors characterized by a storiform or cartwheel-like growth pattern, which were believed to be derived from histiocytes on the basis of early tissue culture studies demonstrating ameboid movement and phagocytosis of explanted tumor cells

Jellouli N, Ben Jouira H, Skouri H, Ghorbel A, Gourgouri A, Mliki : A Proteomic analysis of Tunisian grapevine cultivar Razegui under salt stress