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1), including four enzymes involved in production of TMA, choline-TMA lyase (cutC/D) (Craciun et al., 2014), carnitine monooxygenase (cntA/B) (Zhu et al., 2014), betaine reductase (Andreesen, 1994), and TMAO reductase (Pascal et al., 1984)

The action potential duration to 30% repolarised (APD 30 ), APD 50 , and APD 90 were assessed at the end of the equilibration period, following 5 min of perfusion with 100 M TMAO, and again at the end of a 5-min washout with the NT solution (Figures 5A,B)

D., Prescott, R

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