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in human pharmacokinetic work its half-life is around two hours, with GH peaking near 40 minutes and returning to baseline within a few hours

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It also plays a major role in Phase II liver detoxification, where it binds to and helps eliminate unwanted chemicals and toxins from the body

Recent studies evaluating the effects of LY379268 on reinstatement of drug seeking in squirrel monkeys highlight the concept that activation of group II mGlu receptors may differentially reduce drug seeking depending on the specific drug of abuse and the type of reinstatement paradigm