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Description
The catalytic mechanism of GSTZs differs from other GSTs in that GSH is initially conjugated to the cis double bond of maleylacetoacetate allowing the isomerisation reaction, before being eliminated in a second step allowing the formation of fumarylacetoacetate (Thom et al., 2001)
Study participants were female patients ages 18 years and older who presented with confirmed bilateral symmetrical epidermal melasma through the conduction of a Woods light examination
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