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Since its approval, 13 analogs have been evaluated in clinical trials, but only one, carboplatin, has achieved worldwide acceptance, due to its reduced side-effects, although being less effective, with the clinical standard dosage of carboplatin being a 4:1 ratio compared to cisplatin 23
Increasing the concentration of hydrogen peroxide in the tumor can effectively promote CDT, and there are two main methods to achieve this (Figure 7a)
Amenta, V., Aschberger, K., Arena, M., Bouwmeester, H., Moniz, F
This can cause a slight backup in the veins, resulting in dilated blood vessels
