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The disturbance of iron homeostasis was observed in a murine model and it has since been suggested that the inhibition of axonal transport iron, perturbation of proteins adjusting the iron influx, and elevation of mitochondrial iron storage in neurons and glia lead to iron accumulation in SOD1 transgenic mice 37
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When given NAC, IL-2, and IL-12 there was an increase in the cell surface expression of FasL and CD40L on the NK cells which play an important role in signaling apoptosis of cells infected with M
doi: 10.1007/s11906-020-1031-y Gunnarsson TP, Ehlers TS, Fiorenza M, Nyberg M, Bangsbo J