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They further proposed that NOS mRNA is also a factor involved in the process of oxidative stress in patients with cortical cataracts and has a certain effect on the progression of cataracts

Metformin, through the induction of 5' AMP-activated protein kinase and subsequently insulin sensitivity, has been widely used as a therapeutic agent in various conditions, including type 2 diabetes mellitus, PCOS and gestational diabetes (Reference Rice, Elia and Jawad42)

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Melanogenesis research has documented Melanotan 1s stimulation of eumelanin synthesis in melanocyte cell models and pre-clinical animal studies characterising the pathway from MC1R activation through MITF-driven tyrosinase upregulation to increased melanin production and transfer to keratinocytes