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According to Bland and Altman, the mean difference within 95% of the confidence intervals is 1.96 standard deviations

doi: 10.1046/j.1600-6135.2003.00277.x

These effects may be mediated through glial and anti-inflammatory mechanisms, contributing to the neuroprotective properties of rapamycin (Figure A)

In addition, the altered structure of the DNA makes it unrecognisable by DNA-damage-repair proteins
