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Description
Given that SDH oxidizes succinate to fumarate while reducing CoQ 10 , one might predict that it functions similarly to other mitochondrial CoQ 10 oxidoreductases in suppressing ferroptosis by promoting ubiquinol (CoQ 10 H 2 ) production
(12) Ibuprofen Could Harm the Liver, Kidneys, and Immune Function Ibuprofen damages the liver and raises levels of the enzymes AST, ALT, ALF, and bilirubin
Mutation of this enzyme leads to fumarate accumulation not only in skin cancer and uterine leiomyomas but also in breast, bladder, and Leydig cell tumors 130
2, Supplementary Table 1, and Supplementary Figs
