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Intraperitoneal administration of tumor cells in association with bromelain and NAC showed that bromelain/NAC as a single agent or combination treatment on alternate days inhibited tumor growth and the number of peritoneal nodules in a dose-dependent manner (82)
The compounds, 63 and 64 , showed IC 50 values of 0.16 and 0.085 M, respectively (Figure 19)

These products are not licensed medicines in the UK and are generally sold as food supplements regulated primarily under food law by the Food Standards Agency, though their classification can depend on presentation and claims made
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