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This structural variety enables them to regulate glucose metabolism through a broader array of pathways, offering increased possibilities for T2DM intervention

Indeed, Genestier and colleagues have reported that methotrexate diminishes antigen-stimulated T-cell proliferation both in vitro and in T cells taken from patients taking methotrexate [24]

10.3389/fonc.2021.633210 71 MeyerN.HenkelL.LinderB.ZielkeS.TascherG.TrautmannS.et al (2021)
[DOI] [PubMed] [Google Scholar] 25.Szelag M., Mikulski D., Molski M
