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Rather paradoxically, it has also been highlighted that GSHand notably its catabolites, as originated by metabolism by gamma-glutamyltransferasecan promote oxidative processes, by participating in metal ion-mediated reactions eventually leading to formation of reactive oxygen species and free radicals

Moyad MA (2001) An introduction to aspirin, NSAids, and COX-2 inhibitors for the primary prevention of cardiovascular events and cancer and their potential preventive role in bladder carcinogenesis: part II

This study suggests that a low-dose agonist similar to the dose of endogenous cannabinoids promotes cancer progression
