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Despite the first publication of this finding by Kuzminski in 1998, (5) a survey of Canadian physicians in 2007 revealed that 5.6% used oral vitamin B12 as an alternative to intramuscular injections and that only 25% of physicians were aware of the published trial

While an ideal platelet concentration for PRP is between 2-5 times the levels found in the body, some studies say that PRF products contain approximately 10 times the platelet concentration naturally present
B12 injections can help alleviate these symptoms and provide a range of other benefits, including increased energy levels, improved mood, and better sleep quality

The majority of reports of nausea, vomiting, and/or diarrhea occurred during dose escalation and decreased over time
