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A basket study that implements multiple independent two-stage designs will have a much higher false-positive rate than a typical phase II study and therefore a higher likelihood of being declared effective in at least one basket when in fact the drug is truly ineffective [132]

Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer

Potential mechanisms mediating the protective effects of a peptide from walnut ( Juglans mandshurica maxim.) against hydrogen peroxide induced neurotoxicity in PC12 cells [10.1039/C8FO02557F]

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