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The mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episode syndrome-associated human mitochondrial tRNALeu(UUR) mutation causes aminoacylation deficiency and concomitant reduced association of mRNA with ribosomes

It is interesting that, same as P2Y12 blockers, Ticagrelor and Clopidogrel have the opposite role in ER stress and eNOS phosphorylation

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