glutathione parkinsons disease therapy Parkinson's Cell Non-oral dopaminergic therapies for Parkinson's
Description
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A novel assay that measures the GGT hydrolysis reaction at physiological pH and osmolarity has shown that the second order rate kinetics for GSH and glutathione S -conjugates are similar (Wickham et al., 2011)
Elevated extracellular glutamate impairs System Xc- function, depleting GSH and inducing ferroptosis
doi: 10.1084/jem.20181965
