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Ex vivo analysis confirmed an eight-fold increase in the signal-enhanced retention in the mouse brain relative to other organs (70)

The characteristics of particles were identified by different techniques such as FE-SEM, EDX, TEM, XRD, FT-IR, ICP-AES, and VSM

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Proinflammatory and phagocytic M1 macrophages (arising after exposure to TNF, LPS or IFN, and secreting TNF, IL-1, IL-6), which are initially present in the damaged tissue, are followed by a second wave of anti-inflammatory M2 macrophages (developing after stimulation with IL-10, and releasing IL-10, TGF-, IGF-1)