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doi: 10.1155/2018/4051232
Conclusions The antagonistic pleiotropy in the function of the insulin/IGF-1 pathway reveals a paradox of the aging process since insulin/IGF-1 signaling is an important signaling pathway of growth and differentiation during development but its function accelerates the aging process later in the lifespan

The NADPH oxidase nox4 controls macrophage polarization in an NFB-dependent manner

Ocrelizumab versus interferon beta-1a in relapsing multiple sclerosis
