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doi: 10.3389/fnut.2025.1686056 Received 14 August 2025 Accepted 25 September 2025 Published 16 October 2025 Volume 12 - 2025 Edited by Mingyue Song, South China Agricultural University, China Reviewed by Ludovica Verde, University of Naples Federico II, Italy Arely Vergara-Castaeda, La Salle University of Northwest, Mexico Updates Copyright 2025 Chyliska and Maciejczyk

Other Contributing Factors Smoking and tobacco use Iron or Vitamin B12 deficiency Allergic reactions to toothpaste or skincare products Excessive caffeine intake 5 Home Remedies to Lighten Darkness Around Lips Natural remedies can be incredibly effective when used consistently

Here is what you need to know: What is methylmalonic acid, and why does it matter

They have a wide range of drug segments and adhere to international quality standards