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1A, Supplementary Data 3)

Some of the numerous benefits of a B-complex and NAD infusion include improved metabolism and fat reduction, increased energy due to greater red blood cell production, better mood, and overall improved mental acuity and physical performance

Moreover, GLP-1R cascade also has interactions to regulatory proteins involved in the insulin receptor cascades such as the insulin receptor substrates (IRS) and the PI3K involved in the positive regulation for survival, metabolism and proliferation of beta pancreatic cells as well as apical glucose transport in peripheral tissues

Nevertheless, there have been few investigations into the use of CRISPR-Cas9 in folate biofortification, so further research is required to assess the potential benefits and risks associated with this application