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As been asserted, carbidopa causes irreversible binding of PLP and PLP-dependent enzymes depleting PLP bodily stores (70, 71)

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Salts, esters, amides, prodrugs and other derivatives of the active agents can be prepared using standard procedures known to those skilled in the art of synthetic organic chemistry and described, for example, by March (1992) Advanced Organic Chemistry

Presently, a growing amount of research has indicated that plant-derived natural products may significantly alleviate the progression of thrombotic disorders due to the affordability, high safety, and multiple targets