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doi: 10.1016/0005-2736(76)90160-7 78 ColeSPCBhardwajGGerlachJHMackieJEGrantCEAlmquistKCet al

1% with placebo

Mechanistically, the pathway is relatively well-mapped: semaglutide reduces fasting insulin lowers LH-mediated ovarian androgen secretion increases SHBG, which binds and inactivates free testosterone creates a more favorable hormonal environment in the follicle
