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Additionally, AGEs activate the TGF- signaling pathway and inhibit endothelial cell VEGFR2 expression, leading to endothelial cell injury [82]
Accordingly, glutathione, its precursors, and/or metabolites serve as biomarkers of disease risk, therapeutic targets, and measures of treatment response
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Similarly, pharmacokinetics of ezetimibe glucuronide in human subjects with OATP1B1 polymorphism was affected
