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"When consumed in moderate amounts of 200-300 milligrams per day in the form of food or beverages (equivalent to about two 8-ounce cups of brewed coffee), it is considered socially acceptable and safe

Kotronakis I

Such rhythm persists when the influence of the environmental/behavioral cycles are removed, indicating circadian regulation [33]

For racing pigeons, this process is particularly important because long-distance flight relies heavily on fat metabolism
