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Oral delivery produces slower absorption with sustained but lower peak plasma concentrations, while subcutaneous injection creates rapid peaks within 15-30 minutes followed by faster clearance
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As a matter of fact, APR gene expression or enzyme activity is regulated by many conditions or treatments in which other genes/enzymes are not regulated

Although these agents have been shown to be effective in vitro and in mice bearing drug-resistant human tumors, none thus far have been tested in clinical trials
