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Description
These molecules can interact with DNA and form etheno-DNA adducts, leading to carcinogenesis [62]

Writing-review & editing: SA, CC, CS, and MS

doi:10.1016/j.ecl.2020.10.004 Kulkarni AD, Jamieson DJ, Jones HW, Jr., et al

Conversely, mTORC1, activated by AA-binding proteins such as Sestrin-2 (Leu sensor) and Castor-1 (Arg sensor), promotes anabolic metabolism, translation, and ribosome biogenesis (Saxton et al, 2016a, 2016b
