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McKenna MJ, Medved I, et al
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miR-186 is decreased in aged brain and suppresses BACE1 expression
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The activation of caspase-9 by the release of apoptotic factors, including cytochrome c , from the mitochondria to the cytoplasm due to the loss of MMP is a major initial step in the initiation of a caspase-dependent intrinsic apoptosis pathway [39,40]
