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Understanding how these mutations influence amyloid processing, lipid metabolism and neuroinflammatory responses will be critical for determining their role in modulating susceptibility to late-onset spontaneous Alzheimer-like pathology in this species

An Excel table containing additional information (company name, catalogue number) of all employed commercial reagents is available as Supplementary Data

Human studies have shown that acute exercise can raise MOTS-c levels ~12-fold in skeletal muscle (and about 1.5-fold in circulation), with elevated levels persisting for hours post-exercise

pastoris GS115 ( 3 Metabolic pathways Fat metabolism plays a crucial role in maintaining homeostasis within the body (Figure 2 presents the metabolic pathways of royal jelly acid