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In contrast, methylcobalamin (vitamin B 12 ) interventions produced mixed results, with some RCTs reporting improved clinician-rated outcomes, though pooled effect sizes across studies did not reach statistical significance [25]
The primary mechanism of action involves binding to GLP-1 receptors located throughout the body, particularly in pancreatic beta cells, the gastrointestinal tract, and the central nervous system
It's important to emphasize: virtually all of this research has been conducted in animal models
10.1016/j.regpep.2009.05.008 3 BarisicI.BalenovicD.KlicekR.RadicB.NikitovicB.DrmicD.et al (2013)
