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Normal Physiology of ACTH and GH Release in the Hypothalamus and Anterior Pituitary in Man

When encapsulated, it has to survive the GI tract to produce any systemic effect

The bacterium Lactiplantibacillus plantarum transforms omega- 6 fatty acid linoleic acid (LA) into conjugated linoleic acid (CLA) and oleic acid through a series of enzyme reactions in the gastrointestinal system, simultaneously triggering the NRF2ARE pathway to enhance antioxidant gene activity [154]

This suggests that the modulatory effect of NaBPC157 involves also a substitution of the otherwise prominent insufficient dopamine system
