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Under hypoxic conditions, HIF-1 promotes PD-L1 upregulation, reinforcing immune evasion through both metabolic and immunoregulatory mechanisms [84]

Gremlin 1, frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis

Sensors 3 , 276284 (2003)

[PubMed: 27981615] 16
