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Experiments showed that GSTP1 knockout mice had substantially lower overall protein glutathionylation levels than wild-type mice [84]
Huang SH, Cao XJ, Liu W, Shi XY, Wei W
This may result in an excess of reactive oxygen species that could help to explain accelerated ageing in children with Down syndrome
FASEB J 16:12635, PMID: 12060676 Chernyak BV (1997) Redox regulation of the mitochondrial permeability transition pore
