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Furthermore, the use of iron chelators reduces -syn mRNA expression in HEK293 cells (Li et al

doi: 10.1021/acsanm.1c00394

Dosage: Loading phase of 2-2.5 mg twice per week for 4-6 weeks, then maintenance at 2 mg/week

Notably, the AKT inhibitor MK-2206 completely abolished the protective effects induced by CGA, whereas the AKT activator SC79 further enhanced these effects, providing additional evidence for the critical role of this pathway