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In the UK alone, it results in 82,00090,000 hospital presentations per year [2]
Disruption of the epithelial barrier can 1) affect efficient nutrient absorption, 2) facilitate pathogen translocation into the bloodstream and cause systemic inflammation, and 3) alter gut microbiota composition [1]
PMID 8135427
Many teenagers with polycystic ovary syndrome have insulin resistance and high insulin levels [39]
