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According to Rita Balice-Gordon, CEO of Muna Therapeutics, small molecules that work differently than antibodies might be a better bet
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doi:10.1016/j.bbadis.2013.09.007 Snow BJ, Rolfe FL, Lockhart MM, Frampton CM, OSullivan JD, Fung V, Smith RA, Murphy MP, Taylor KM
While mathematically correct, in practice, we never see values outside of the 014 range
