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Real-world data from clinics offering this combination protocol suggests enhanced fat loss compared to tirzepatide alone, but these observations come from uncontrolled clinical settings and cannot substitute for randomized controlled trials
Kamal M, Mohamed ASR, Fuller CD, Sturgis EM, Johnson FM, Morrison WH, Gunn GB, Hutcheson KA, Phan J, Volpe S, Ng SP, Ferrarotto R, Frank SJ, Skinner HD, Rosenthal DI , Garden AS
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Additionally, such doses might reduce the efficacy of chemotherapy or radiotherapy by counteracting the oxidative stress needed to target cancer cells [20]