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Expanded MSCs at P3 were inferior to freshly isolated bone marrow mononuclear cells in chondrogenesis and cartilage repair, in parallel with decreased telomerase activity, changed chromosomal morphology, downregulated cell cycle, DNA replication and mismatch repair (MMR) pathways [69]

Linoleic Acid Metabolite Leads to Steroid Resistant Asthma Features Partially through NF-B

Note: Drugbank and Pubchem databases were used to obtain natural compounds used in clinical studies

Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study