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In support of a key role of NF-B in the regulation of astrocyte homeostasis and the pre-disposition to detrimental post-traumatic responses, recent studies showed that transcriptional changes underlying astrocyte reactivity can be highly heterogeneous in different neuropathological conditions and depend on context-specific transcription factor crosstalk 9,17

Five reported GSH conjugates of reactive metabolites are produced from troglitazone after incubation with liver microsomes, NADPH, and GSH in a GSH concentration-dependent manner [88]

Forty-two four-week-old male Sprague-Dawley (SD) rats were divided into seven groups: anti-LOX, control, VED, HCG, anti-LOX and VED, VED and HCG, and VED+HCG+anti-LOX

DiPasquale, D