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In our studies, we defined a pathway comprises the UPS and GSH homeostasis that is epistatically regulated by loss of pink-1

10.1016/j.fob.2014.05.002 FEBS Open Bio 79 Reidy-LagunesD

Through systematic mutagenesis and functional studies, we identified the key residues underlying the higher binding affinity of Anamorelin compared to Macimorelin

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