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Description
doi: 10.1158/0008-5472.CAN-04-1906
Neutral pH buffers (PBS, HEPES) are generally compatible with AOD9604 structural stability, but salt, detergent, or protein components can alter binding behavior, chromatographic retention, and ionization efficiency in MS
a IMGN 853 uses sulfo-SPDB linker It was discovered that the unhindered disulfide-bond of DM1 was too unstable in plasma leading to fast plasma clearance with undetectable levels of ADC by day 3
Powerful Antioxidant Support for Detox, Immunity & Cellular Protection|
