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Study participants with Parkinsons disease, who had intramuscular injections of thiamine twice per week, experienced a 49% improvement in overall function and a 55.5% decrease in fatigue

Thus the best-known "function" of B 12 (that which is involved with DNA synthesis, cell division, and anemia) is a facultative function that is mediated by B 12 -conservation of an active form of folate which is needed for efficient DNA production

Second, it is a treatment option to relieve pain and reduce inflammation

It is a coenzyme your cells already make from vitamin B3, and it is central to two things: shuttling electrons through energy metabolism, and serving as a required cofactor for sirtuins, PARPs, and CD38