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At the end of the experiment, the mixture was quenched using the extraction solution for metabolomics (see above) and the extracts were spun down at maximum speed for 10 min

The suprachiasmatic nucleus interacts with regulatory mechanisms and is most likely responsible for disturbances in the main circadian clock function, playing a significant role in sleep-wake disorders

Gene therapy for CFTR repair As a monogenic disease, CF is an obvious candidate for gene therapeutic approaches

It modulates matrix metalloproteinases (MMPs) alongside their tissue inhibitors (TIMPs), creating balanced extracellular matrix remodeling rather than simply suppressing collagen degradation