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These findings manifest PI3K/Akt/mTOR inhibition as a potent strategy to counteract EMT-driven metastasis

The increased energy demand may override the anorexic stimuli (164)

A common genetic mutation of the methyltetrahydrofolate reductase ( MTHFR ) gene that impairs folate metabolism and often leads to high homocysteine levels has been linked to increased risk of migraines, especially migraines with aura (Sudershan 2023

The transformation of cholesterol into bile acids in the liver, via the classical pathway that produces 12-hydroxy bile acids (cholic acid) catalyzed by CYP8B1 and the alternative pathway that yields non-12-hydroxy bile acids (chenodeoxycholic acid) catalyzed by CYP7B1, constitutes the primary cholesterol metabolism route (136)