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Antiaging drugs often work by promoting cell repair and delaying apoptosis, but excessive inhibition of apoptosis or enhanced proliferation may lead to the survival and accumulation of abnormal cells, such as cancer cells

22,23 Patients with rheumatologic conditions, including rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis, may also have fibromyalgia, although the symptom overlap makes a diagnosis challenging

While the treatment for pruritus stemming from cholestatic liver disorders is established, pruritus originating from non-cholestatic causes is frequently encountered in cirrhotic patients due to various non-cholestatic factors

upon inspecting the proteomic datasets, we identified numerous serum proteins, including apolipoproteins (APOA1, APOA4, APOC3 and APOD), hormones (the IGFs) and serine protease inhibitors (A1AT, AT, C1-inhibitor, etc.) (Fig
